Reactions of, B-spiroepoxy-alkannans part IV+ New and facile synthesis of tetrahydric-naphthalin-2-01 derivatives for biological evaluation

Spirooctanones II react with acetoacetanilide to form tetrahydro-naphthalene derivatives IIIa,b, which react with phosphorus oxychloride to give the corresponding chloro derivatives IV. Compounds IV react with hydrazine hydrate, aniline, and hydroxylamine to give the corresponding compounds V, VI and VII, respectively. Compounds V condensed with aromatic aldehydes to give the corresponding hydrazones VIII

Ceanofendl in pentatate: a new aryltetralin from ceanothus Fendleri

A new aryltetrahydronaphthalene derivative, 4-[2',4',6'- triacetoxyphenyl]-5,6,7-trimethyl-1 alpha, 2 beta- diacetoxy-4-hydroxy-1,2,3,4-tetrahydronaphthalene, ceanofendlin pentaacetate, was isolated from the acetylated ethyl acetate extract of Ceanothus fendleri, Rhamnaceae. The known flavonoids kaempferol, kaempferol-3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside, kaempferol-3-O-rutinoside, quercetin-3-O-rutinoside [rutin] and quercetin-3-O-alpha-L-rhamnopyranosyl-[1-6]-O-beta-D-galactopyranoside were also obtained. The structural characteristics of these compounds were confirmed by spectroscopic methods